Imipenem Drug Combination Cilastatin FDA Link

Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.

Also Known As:

Primaxin; Cilastatin, Imipenem Drug Combination; Imipenem - Cilastatin; Imipenem - Cilastatin Sodium; Imipenem Cilastatin; Imipenem Cilastatin Sodium; Imipenem-Cilastatin; Imipenem-Cilastatin Sodium; Imipenem-Cilastatin, Sodium Salt; MK 0787-MK 0791 mixture; MK 787-MK 791 mixture; Thienam; Tienam 500; Zienam; Cilastatin, Imipenem; Imipenem Cilastatin, Sodium Salt; MK 0787 MK 0791 mixture; MK 787 MK 791 mixture

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - beta-Lactams: 2386
      - Carbapenems: 4837
        Thienamycins: 1
        Imipenem: 1684
        Imipenem Drug Combination Cilastatin: 736
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclopropanes: 9
        Cilastatin: 128
        Imipenem Drug Combination Cilastatin: 736
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - beta-Lactams: 2386
      - Carbapenems: 4837
        Thienamycins: 1
        Imipenem: 1684
        Imipenem Drug Combination Cilastatin: 736
Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Monounsaturated Fatty Acids: 676
      - Cilastatin: 128
        Imipenem Drug Combination Cilastatin: 736
Pharmaceutical Preparations
- Drug Combinations: 5337
  - Imipenem Drug Combination Cilastatin: 736

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Disease

Drug/Important Bio-Agent (IBA)